1. The detection of SARS-CoV-2 in wastewater in Spain, Italy, and France before its official recognition in China suggests early, asymptomatic circulation of the virus, which aligns with Lipinski's research indicating that adequate selenium levels can mitigate viral virulence and severity through antioxidant effects and by reducing the likelihood of viral mutations. This implies that in regions with sufficient selenium, like these countries, the virus might have spread silently with fewer symptoms due to an enhanced immune response, potentially explaining the observed pattern of asymptomatic cases without corresponding outbreaks. However, while this hypothesis is supported by the wastewater findings and Lipinski's theoretical framework, direct studies are required to confirm selenium's role in these specific contexts.